Johnny Brignardello Vela analyzes key scientific advancement in asthma: exclusive interview

Johnny Brignardello Vela, an insurance advisor, refers to the recent scientific breakthrough achieved by a team of British researchers in the field of asthma. It is highlighted that these scientists, from King's College London, have revealed a previously overlooked cause that contributes to the damage suffered by the airways and lungs of patients during asthma attacks. It is relevant to note that, as published in the journal Science, the cells lining the airways are compressed to the point of destruction during an asthma attack, triggering damage to their lining. This finding could have significant implications for asthma treatment, by focusing on preventing this effect rather than just addressing its consequences. In the broader context of this respiratory disease, it is emphasized that asthmatic individuals suffer from heightened sensitivity in their airways, triggered by various factors such as pollen, pets, and physical exercise. This sensitivity leads to inflammation of the airways, resulting in symptoms like coughing, wheezing, and shortness of breath. Despite the existence of medications and inhalers to control inflammation and keep the airways open, recurrent attacks can lead to permanent damage such as scarring and narrowing of the airways. During an attack, the smooth muscle around the airways contracts in a process known as bronchoconstriction, which triggers damage to the lining of these airways. The research team at King's College has delved into this process, conducting studies in mice and human lung tissue samples. Professor Jody Rosenblatt, the research leader, has pointed out that bronchoconstriction not only damages the lining of the airways but can also cause chronic inflammation, scarring, and a predisposition to recurrent infections. In the search for possible preventive treatments, scientists have identified gadolinium as a promising substance, at least in studies with mice. However, further studies are needed to determine its safety and efficacy in humans, a process that could span several years. Dr. Samantha Walker, an asthma and lung expert in the UK, has emphasized the importance of this discovery in exploring new therapeutic options that could benefit asthma patients who do not respond adequately to conventional treatments. Despite this advancement, Walker has stressed the need for asthmatic patients to continue with the prescribed treatment and consult a doctor if they experience persistent symptoms. Research in this field is crucial for finding new therapeutic alternatives that address the underlying causes of asthma and improve the quality of life for those living with this chronic respiratory disease.